A voxel-based morphometry and diffusion tensor imaging analysis of asymptomatic Parkinson's disease-related G2019S LRRK2 mutation carriers.
Identifieur interne : 000679 ( Main/Exploration ); précédent : 000678; suivant : 000680A voxel-based morphometry and diffusion tensor imaging analysis of asymptomatic Parkinson's disease-related G2019S LRRK2 mutation carriers.
Auteurs : Avner Thaler [Israël] ; Moran Artzi ; Anat Mirelman ; Yael Jacob ; Rick C. Helmich ; Bart F L. Van Nuenen ; Tanya Gurevich ; Avi Orr-Urtreger ; Karen Marder ; Susan Bressman ; Bastiaan R. Bloem ; Talma Hendler ; Nir Giladi ; Dafna Ben BashatSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- Adult, Brain (pathology), Cognition Disorders (etiology), Cognition Disorders (genetics), Diffusion Tensor Imaging, Female, Glycine (genetics), Humans, Male, Middle Aged, Parkinson Disease (complications), Parkinson Disease (genetics), Parkinson Disease (pathology), Protein-Serine-Threonine Kinases (genetics), Serine (genetics), Severity of Illness Index.
- MESH :
- chemical , genetics : Glycine, Protein-Serine-Threonine Kinases, Serine.
- complications : Parkinson Disease.
- etiology : Cognition Disorders.
- genetics : Cognition Disorders, Parkinson Disease.
- pathology : Brain, Parkinson Disease.
- Adult, Diffusion Tensor Imaging, Female, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
Patients with Parkinson's disease have reduced gray matter volume and fractional anisotropy in both cortical and sub-cortical structures, yet changes in the pre-motor phase of the disease are unknown.
DOI: 10.1002/mds.25827
PubMed: 24482120
Affiliations:
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Le document en format XML
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<author><name sortKey="Thaler, Avner" sort="Thaler, Avner" uniqKey="Thaler A" first="Avner" last="Thaler">Avner Thaler</name>
<affiliation wicri:level="1"><nlm:affiliation>Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler School of Medicine, Sagol School for Neuroscience, Tel Aviv University, Tel Aviv, Israel.</nlm:affiliation>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<front><div type="abstract" xml:lang="en">Patients with Parkinson's disease have reduced gray matter volume and fractional anisotropy in both cortical and sub-cortical structures, yet changes in the pre-motor phase of the disease are unknown.</div>
</front>
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<affiliations><list><country><li>Israël</li>
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